简介：Darunavir ethanolate (TMC114 ethanolate) 是一种用于治疗和预防HIV/AIDS的HIV蛋白酶抑制剂。对野生型HIV-1蛋白酶的Ki值为1 nM。

地瑞那韦乙醇盐物理化学性质：

地瑞那韦乙醇盐详细介绍：

地瑞那韦乙醇盐参考文献：

[1]. Tie Y, et al. High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains. J Mol Biol. 2004 Apr 23;338(2):341-52.

[2]. McKeage K, et al. Darunavir: a review of its use in the management of HIV infection in adults. Drugs. 2009;69(4):477-503.

[3]. Bhalekar MR, et al. In-vivo bioavailability and lymphatic uptake evaluation of lipid nanoparticulates of darunavir. Drug Deliv. 2016 Sep;23(7):2581-2586.

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